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MIF demonstrates chemokine-like functionality and was discovered as a ligand of equally CXCR2 and CXCR4. Binding of MIF to those receptors improves monocyte recruitment and leukocyte chemotaxis (determine 1). In human chondrosarcoma cells, this recruitment is mediated by Gαi proteins and PI3K in T mobile adhesion by way of upregulation of the tran
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